PIMA532892
IL-31 Monoclonal Antibody (B7-B0), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532892-Each-of-1 | In Stock | ₹ 50,418.50 |
PIMA532892 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,418.50
GST (18%): ₹ 9,075.33
Total Price: ₹ 59,493.83
Antigen
IL-31
Classification
Monoclonal
Concentration
2 mg/mL
Formulation
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q6EBC2
Gene Symbols
Il31
Immunogen
Recombinant protein within Human Interleukin 31 aa 1-164
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Applications
ELISA, Western Blot
Clone
B7-B0
Conjugate
Unconjugated
Gene
Il31
Gene Alias
1700013B14Rik, IL31, IL-31, ILN, Interleukin, interleukin 31, interleukin-31
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
386653
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Mouse Monoclonal Antibody Interleukin-31 (IL-31) is a recently discovered T-cell cytokine closely related to IL-6 type cytokines and is preferentially produced by T helper type 2 cells
- IL-31 activity is mediated through the ligand-induced oligomerization of a dimeric receptor complex containing IL-31 receptor A and oncostatin M receptor
- In response to IL-31 binding, these proteins activate the JAK/STAT and the AKT signaling pathways
- RNA levels of IL-31 receptor A and oncostatin M receptor are induced in activated monocytes but are expressed constitutively in epithelial cells
- IL-31, when overexpressed in transgenic mice, results in the development of pruritis, alopecia, and skin lesions and in humans may result in atopic dermatitis, suggesting that IL-31 may represent a novel target for antipruritic drug development.