PIMA532263
IRAK-M Recombinant Rabbit Monoclonal Antibody (SN64-07), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532263-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532263 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
IRAK-M
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q9Y616
Gene Symbols
IRAK3
Immunogen
Synthetic peptide within Human IRAKM aa 547-596
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Clone
SN64-07
Conjugate
Unconjugated
Gene
IRAK3
Gene Alias
4833428C18Rik, AI563835, ASRT5, FLJ13601, IL-1 receptor-associated kinase M, interleukin 1 receptor associated kinase 3, interleukin-1 receptor-associated kinase 3, IRAK3, IRAK-3, IRAKM, IRAK-M
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
11213
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- IRAK3 serine/threonine kinase or interleukin-1 receptor-associated kinase 3 is a member of the interleukin-1 receptor-associated kinase protein family which are essential components of the Toll/IL-R immune signal transduction pathways
- IRAK3 is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling
- IRAK3 mediates critical aspects of innate immunity that result in an immunocompromised state during sepsis
- Mutations in IRAK3 are associated with a susceptibility to asthma.