PIMA533010

Fumarase Monoclonal Antibody (9D8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA533010-Each-of-1 In Stock ₹ 47,481.50

PIMA533010 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

Fumarase

Classification

Monoclonal

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.

P07954, P14408, P97807

Gene Symbols

FH, Fh1

Immunogen

A synthetic peptide corresponding to a sequence of human FH (YDKAAKIAKTAH KNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG2a

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

9D8

Conjugate

Unconjugated

Gene

FH

Gene Alias

EF-3, Fh, Fh1, Fh-1, FMRD, fumarase, fumarate hydratase, fumarate hydratase 1, fumarate hydratase, mitochondrial, HLRCC, LRCC, MCL, MCUL1

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14193, 14194, 2271, 24368

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • The protein encoded by this gene is an enzymatic component of the tricarboxylic acid cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate
  • It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used
  • The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm
  • It is similar to some thermostable class II fumarases and functions as a homotetramer
  • Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.