PIMA533082

H3K4me3 Recombinant Rabbit Monoclonal Antibody (RM137), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA533082-Each-of-1 In Stock ₹ 50,774.50

PIMA533082 - Each of 1

₹ 50,774.50

In Stock

Quantity

1

Base Price: ₹ 50,774.50

GST (18%): ₹ 9,139.41

Total Price: ₹ 59,913.91

Antigen

H3K4me3

Classification

Recombinant Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.

P68431, P68433, P84228, Q71DI3

Gene Symbols

H3C1, H3C10, H3C12, H3C14, H3C15, H3C2, H3C7

Immunogen

A trimethyl-peptide corresponding to Trimethyl-Histone H3 (Lys4).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Dot Blot, ELISA, Luminex, Western Blot

Clone

RM137

Conjugate

Unconjugated

Gene

H3C1

Gene Alias

B0035.7, BUR5, CELE_T10C6.12, CG31613, CG31613-PA, CG33803, CG33806, CG33809, CG33812, CG33815, CG33818, CG33821, CG33824, CG33827, CG33830, CG33833, CG33836, CG33839, CG33842, CG33845, CG33848, CG33851, CG33854, CG33857, CG33860, CG33863, CG33866, Dmel\CG31613, Dmel_CG31613, F07B7.10, F07B7.3, F08G2.2, F17E9.13, F35H10.1, F45F2.4, F54E12.5, F55G1.10, H02I12.7, H3, H3 histone, H3 histone family, member A, H3 histone family, member I, H3 histone family, member K, H3 histone family, member L, H3 histone family, member M, H3 histone, family 2, H3 histone, family 3A, H3 histone, family 3B, H3 histone, family 3B (H3.3B), H3 histone, family 3B.1, H3 histone, family 3C, H3 K4, H3.1-221, H3.1-291, H3.1-I, H3.2, H3.2-221, H3.2-614, H3.2-615, H3.2-616, h3.2a, H3.3A, H3.3B, H3.5, H3/A, H3/b, H3/d, H3/f, H3/i, H3/j, H3/k, H3/l, H3/M, H3/n, H3/o, H3-143, H3-291, H3-3A, H3-3b, h3-5, H3-53, H3-614, H3a, H3b, H3-B, H3C1, H3C10, H3C11, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, H3c8, H3f, H3-F, H3F1K, H3F2, H3F3, h3f3a, H3F3B, h3f3b.1, H3F3C, h3f3d, H3FA, H3FB, H3FC HIST1H3C, H3FD, H3FF, H3FH, H3FI, H3FJ, H3FK, H3FL, H3FM, H3FN, H3g, H3h, H3i, H3K4, H3Lys4me3, h3r, HHT1, HHT2, his-12, his-16, his-19, his-21, His3, his-3, His3:CG31613, His3:CG31613-PA, His3:CG33803, His3:CG33806, His3:CG33809, His3:CG33812, His3:CG33815, His3:CG33818, His3:CG33821, His3:CG33824, His3:CG33827, His3:CG33830, His3:CG33833, His3:CG33836, His3:CG33839, His3:CG33842, His3:CG33845, His3:CG33848, His3:CG33851, His3:CG33854, His3:CG33857, His3:CG33860, His3:CG33863, His3:CG33866, his-30, his-33, his-43, his-47, his-51, his-53, his-57, his-61, his-65, his-68, his-7, Hist1, Hist1h3a, HIST1H3B, Hist1h3c, Hist1h3d, HIST1H3E, Hist1h3f, hist1h3g, hist1h3g.L, HIST1H3H, Hist1h3i, HIST1H3J, hist2h3, HIST2H3A, Hist2h3b, HIST2H3C, Hist2h3c1, Hist2h3c2, Hist2h3c2-ps, Hist2h3ca1, Hist2h3ca2, HIST2H3D, histone 1, H3a, histone 1, H3b, histone 1, H3f, histone 1, H3h, histone 2, H3a, histone 2, H3c, histone 2, H3c2, histone 2, H3ca2, Histone 3, histone cluster 1, H3a, histone cluster 1, H3b, histone cluster 1, H3f, histone cluster 1, H3g protein L homeolog, histone cluster 1, H3h, histone cluster 2, H3a, histone cluster 2, H3c, histone cluster 2, H3c2, histone cluster 2, H3c2, pseudogene, histone gene complex 1, Histone H2A, Histone H3, histone H3.1, Histone H3.2, histone H3.3, Histone H3.3C, histone H3.5, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, histone H3/l, Histone H3/m, histone H3/o, Histone H3K4me3, histone variant H3.5, hypothetical protein LOC550262, K06C4.11, K06C4.3, M32461, methyl Histone 3, methyl Histone H3, N2749, PP781, SIN2, T10C6.12, T23D8.6, Trimethyl H3, Tri-methyl H3, Trimethyl Histone H3, Tri-methyl Histone H3, Tri-Methyl-H3 K4, Tri-Methyl-H3 Lys4, Tri-Methyl-Histone H3 K4, Tri-Methyl-Histone H3 Lys4, wu:fa25h06, wu:fa96g06, wu:fb07a08, wu:fb36f01, XELAEV_18028537mg, YBR010W, YBR0201, YNL031C, zgc:110292, zgc:174300, zgc:56193, zgc:56418, zgc:64222, zgc:86731, ZK131.10, ZK131.6

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

126961, 260423, 319150, 319152, 333932, 360198, 8350, 8356, 8357, 8358, 8968, 97114

Content And Storage

-20°C

Form

Liquid

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Description

  • Specificity: reacts to Histone H3 trimethylated at Lysine 4 (K4me3)
  • No cross reactivity with monomethylated Lysine 4 (K4me1) or dimethylated Lysine 4 (K4me3), or other methylation in histone H3
  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells
  • H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome
  • Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability
  • Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors
  • The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes
  • These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.