PSMA Recombinant Rabbit Monoclonal Antibody (RM327), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533086-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA533086 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
PSMA
Classification
Recombinant Monoclonal
Concentration
0.2 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.
Q04609
Gene Symbols
FOLH1
Immunogen
A peptide corresponding to the C-terminus of human PSMA (Prostate-specific membrane antigen).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
RM327
Conjugate
Unconjugated
Gene
FOLH1
Gene Alias
Cell growth-inhibiting gene 27 protein, FGCP, folate hydrolase (prostate-specific membrane antigen) 1, folate hydrolase 1, FOLH, Folh1, Folylpoly-gamma-glutamate carboxypeptidase, GCP2, GCPII, GIG27, glutamate carboxylase II, glutamate carboxypeptidase 2, Glutamate carboxypeptidase II, membrane glutamate carboxypeptidase, mGCP, mopsm, Naalad, NAALAD1, NAALAdase, NAALADase I, N-acetylated alpha-linked acidic dipeptidase, N-acetylated alpha-linked acidic dipeptidase 1, N-acetylated-alpha-linked acidic dipeptidase I, prostate specific membrane antigen, prostate specific membrane antigen variant F, prostate-specific membrane antigen, Prostate-specific membrane antigen homolog, PSM, PSMA, pteroylpoly-gamma-glutamate carboxypeptidase
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
2346
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Specificity: reacts to human PSMA (Prostate-specific membrane antigen)
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family
- The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney
- A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia
- Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity
- In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer
- This gene likely arose from a duplication event of a nearby chromosomal region
- Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.