GFAP Recombinant Rabbit Monoclonal Antibody (RM246), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533059-Each-of-1 | In Stock | ₹ 47,837.50 |
PIMA533059 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,837.50
GST (18%): ₹ 8,610.75
Total Price: ₹ 56,448.25
Antigen
GFAP
Classification
Recombinant Monoclonal
Concentration
0.05 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.
P03995, P14136
Gene Symbols
GFAP
Immunogen
A peptide corresponding to the N-terminus of human GFAP.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
RM246
Conjugate
Unconjugated
Gene
GFAP
Gene Alias
6330404F12Rik, 65 kDa glutamic acid decarboxylase, AI836096, ALXDRD, Astrocyte or Intermediate Filament Protein, cb345, class III intermediate filament protein, etID36982.3, FLJ45472, GAD(65), Gad2, Gad-2, GAD65, GAD-65, GFAP, GFAP epsilon, gfap protein, gfapl, glial fibrillary acidic protein, Glial Fibrillary Acidic Protein (GFAP), glial fibrillary acidic protein alpha, glutamate decarboxylase 2, Glutamate decarboxylase 65 kDa isoform, glutamic acid decarboxylase 2, I79_011607, intermediate filament, intermediate filament protein, intermediate filament protein, GFAP, Unknown (protein for MGC:139638), wu:fb34h11, wu:fk42c12, xx:af506734, zgc:110485, zGFAP, intermediate filament protein, zrf-1 antigen
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
14580, 2670
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Specificity: reacts to human and mouse GFAP (Glial fibrillary acidic protein)
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- GFAP (Glial fibrillary acidic protein) is a member of the class III intermediate filament protein family
- GFAP is heavily and specifically expressed in astrocytes and certain astroglia of the central nervous system, in satellite cells of peripheral ganglia, and in non-myelinating Schwann cells of peripheral nerves
- In addition, neural stem cells strongly express GFAP
- Antibodies to GFAP are very useful as markers of astrocytic cells
- In addition, many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP
- GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes
- GFAP is used as a marker to distinguish astrocytes from other glial cells during development
- Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system
- Alternative splicing of the GFAP gene results in multiple transcript variants encoding distinct isoforms.