PIMA533144

Glypican 3 Recombinant Rabbit Monoclonal Antibody (4H11), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA533144-Each-of-1 In Stock ₹ 50,596.50

PIMA533144 - Each of 1

₹ 50,596.50

In Stock

Quantity

1

Base Price: ₹ 50,596.50

GST (18%): ₹ 9,107.37

Total Price: ₹ 59,703.87

Antigen

Glypican 3

Classification

Recombinant Monoclonal

Concentration

0.33 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P51654

Gene Symbols

GPC3

Immunogen

A synthesized peptide derived from human GPC3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

ELISA, Immunocytochemistry, Western Blot

Clone

4H11

Conjugate

Unconjugated

Gene

GPC3

Gene Alias

defective in Simpson-Golabi-Behmel overgrowth syndrome, DGSX, glypican 3, glypican proteoglycan 3, glypican-3, Glypican-3 alpha subunit, Glypican-3 beta subunit, Gpc3, GTR22, GTR2-2, heparan sulphate proteoglycan, intestinal protein OCI-5, MXR7, OCI5, OCI-5, proteoglycan GPC3, SDYS, secreted glypican-3, SGB, SGBS, SGBS1

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

2719

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

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Description

  • GPC3 is a cell surface proteoglycan that bears heparan sulfate
  • This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function
  • Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage
  • These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition
  • Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS)
  • SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.