HDAC9 Recombinant Rabbit Monoclonal Antibody (1F2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533151-Each-of-1 | In Stock | ₹ 50,596.50 |
PIMA533151 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,596.50
GST (18%): ₹ 9,107.37
Total Price: ₹ 59,703.87
Antigen
HDAC9
Classification
Recombinant Monoclonal
Concentration
1.49 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
Q9UKV0
Gene Symbols
Hdac9
Immunogen
A synthesized peptide derived from human HDAC9
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
1F2
Conjugate
Unconjugated
Gene
Hdac9
Gene Alias
AV022454, D030072B18Rik, DKFZp779K1053, HD7, HD7b, HD9, HDAC, HDAC7, Hdac7b, HDAC9, hdac-9, HDAC9B, HDAC9FL, HDRP, histone deacetylase 4/5-related protein, histone deacetylase 7B, Histone deacetylase 9, histone deacetylase-related protein, KIAA0744, MEF-2 interacting transcription repressor (MITR) protein, MEF2-interacting transcription repressor MITR, Mitr, mKIAA0744, RGD1310748, RGD1563092, TWIST
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
9734
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
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Description
- In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin
- The remodeling of chromatin is a critical component of transcriptional regulation and the acetylation of nucleosomal histones is a major source of this remodeling
- Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA
- Several mammalian proteins function as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP, HAT1 and the TFIID subunit TAF II p250
- Conversely, the deacetylation of histones is associated with transcriptional silencing
- The histone deacetylases (HDAC) include HDAC1-9
- HDAC9 and HDAC9a are two alternatively spliced isoforms of HDAC9
- HDAC9a is 132 amino acids shorter than HDAC9, but both isoforms contain the HDAC catalytic domain, remain capable of deacetylase activity and repress myoctye enhancer-binding factor 2-mediated transcription
- HDAC9 and HDAC9a are expressed in brain, skeletal muscle, kidney, placenta and pancreas.