PIMA533187

Phospho-RNA pol II CTD (Ser2) Recombinant Rabbit Monoclonal Antibody (2G1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA533187-Each-of-1 In Stock ₹ 50,507.50

PIMA533187 - Each of 1

₹ 50,507.50

In Stock

Quantity

1

Base Price: ₹ 50,507.50

GST (18%): ₹ 9,091.35

Total Price: ₹ 59,598.85

Antigen

Phospho-RNA pol II CTD (Ser2)

Classification

Recombinant Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P24928

Gene Symbols

POLR2A

Immunogen

A synthesized peptide derived from human Phospho-POLR2A (S2)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

ChIP Assay, ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

2G1

Conjugate

Unconjugated

Gene

POLR2A

Gene Alias

220kDa, AW321876, DNA polymerase alpha 1 catalytic subunit, DNA polymerase alpha 1, 180 kDa, DNA polymerase alpha 1, catalytic subunit, DNA polymerase alpha catalytic subunit, DNA polymerase alpha catalytic subunit p180, DNA polymerase alpha p180 subunit, DNA polymerase alpha subunit I, DNA polymerase epsilon catalytic subunit, DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A, DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase III largest subunit, DUN2, EC 2.7.7.6, G7a/Bat6Hom, hRPB220, hsRPB1, I79_002751, I79_016081, MGC75453, N0825, NSX, p180, Pol II S2p, POL2, Pola, Pola1, POLR2, POLR2A, POLRA, polymerase (DNA directed), alpha 1, polymerase (DNA directed), alpha 1, catalytic subunit, polymerase (DNA) alpha 1, catalytic subunit, polymerase (DNA-directed), alpha (70kD), Polymerase (RNA II (DNA directed), large polypeptide, polymerase (RNA) II (DNA directed) polypeptide A, polymerase (RNA) II (DNA directed) polypeptide A, 220kDa, polymerase (RNA) II subunit A, POLYMERASE II, polymerase, alpha 1, RNA, RNA POL2, RNA polymerase II 1, RNA polymerase II carboxy-terminal domain, RNA polymerase II C-terminal domain, RNA polymerase II largest subunit, RNA polymerase II subunit A, RNA polymerase II subunit B1, RNA-directed RNA polymerase II subunit RPB1, RP02, Rpb1, RPB220, RPBh1, Rpii215, RpIILS, RPO2, RPO21, Rpo2-1, RPOL2, SUA8, YNL262W

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

5430

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

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Description

  • RNA polymerase II is the enzyme responsible for the synthesis of mRNA and many non-coding RNAs
  • POLR2A encodes RNA polymerase II subunit B1 (RPB1), the largest subunit of RNA polymerase II
  • The C-terminal domain (CTD) of RPB1 contains tandem heptapeptide repeats with the consensus sequence YSPTSPS
  • Phosphorylation and other modifications within this sequence influence the recruitment of factors that regulate the transcription cycle
  • Recruitment of RNA processing factors to the elongation complex is coordinated by the phosphorylation of Serine-2 and Serine-5 residues within the CTD.