Phospho-RNA pol II CTD (Ser5) Recombinant Rabbit Monoclonal Antibody (JM51-21), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532638-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA532638 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
Phospho-RNA pol II CTD (Ser5)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P08775, P24928
Gene Symbols
POLR2A
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Ser5 of Human POLR2A aa 1590-1627
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
JM51-21
Conjugate
Unconjugated
Gene
POLR2A
Gene Alias
220kDa, AW321876, DNA polymerase alpha 1 catalytic subunit, DNA polymerase alpha 1, 180 kDa, DNA polymerase alpha 1, catalytic subunit, DNA polymerase alpha catalytic subunit, DNA polymerase alpha catalytic subunit p180, DNA polymerase alpha p180 subunit, DNA polymerase alpha subunit I, DNA polymerase epsilon catalytic subunit, DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A, DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase III largest subunit, DUN2, EC 2.7.7.6, G7a/Bat6Hom, hRPB220, hsRPB1, I79_002751, I79_016081, MGC75453, N0825, NSX, p180, Pol II S2p, POL2, Pola, Pola1, POLR2, POLR2A, POLRA, polymerase (DNA directed), alpha 1, polymerase (DNA directed), alpha 1, catalytic subunit, polymerase (DNA) alpha 1, catalytic subunit, polymerase (DNA-directed), alpha (70kD), Polymerase (RNA II (DNA directed), large polypept
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
20020, 363633, 5430
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- RNA polymerase II is the enzyme responsible for the synthesis of mRNA and many non-coding RNAs
- POLR2A encodes RNA polymerase II subunit B1 (RPB1), the largest subunit of RNA polymerase II
- The C-terminal domain (CTD) of RPB1 contains tandem heptapeptide repeats with the consensus sequence YSPTSPS
- Phosphorylation and other modifications within this sequence influence the recruitment of factors that regulate the transcription cycle
- Recruitment of RNA processing factors to the elongation complex is coordinated by the phosphorylation of Serine-2 and Serine-5 residues within the CTD.