MASP1 Monoclonal Antibody (2B11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533364-Each-of-1 | In Stock | ₹ 98,968.00 |
PIMA533364 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 98,968.00
GST (18%): ₹ 17,814.24
Total Price: ₹ 1,16,782.24
Antigen
MASP1
Classification
Monoclonal
Concentration
100 μg/mL
Formulation
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.
P48740
Gene Symbols
MASP1
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
5648
Content And Storage
4° C
Form
Liquid
Applications
ELISA, Immunoprecipitation, Western Blot
Clone
2B11
Conjugate
Unconjugated
Gene
MASP1
Gene Alias
3MC1; AW048060; C4/C2 activating component of Ra-reactive factor; CCPII; Complement factor MASP-3; complement-activating component of Ra-reactive factor; Crarf; CRARF1; mannan binding lectin serine peptidase 1; mannan-binding; mannan-binding lectin serine peptidase 1; mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor); mannan-binding lectin serine protease 1; Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain; Mannose-binding lectin-associated serine protease 1; mannose-binding protein associated serine protease-1; mannose-binding protein-associated serine protease; MAP1; MAp44; MASP; MASP1; MASP-1; Masp1/3; MASP3; PRSS5; Ra-reactive factor serine protease p100; raRF; Serine protease 5; serine protease MASP1
Host Species
Mouse
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- Product is supplied at 1 mL (100 μL/mL)
- The antibody recognizes the heavy chain common to both MASP-1 and MASP-3
- Application Notes: Western Blot - Product is useful for Western blotting of non -reduced samples
- The antibody does not work in Western blotting of reduced samples
- Immunoassays - Product can be used as a detection antibody
- MBL is a key component in immune response in that it can directly trigger neutralization of invading microorganisms by an Ab-independent mechanism
- Mutations of human MBL are associated with immunodeficiency resulting from a reduction in the ability of the mutant MBL to initiate complement fixation
- In human, three types of MBL-associated serine proteases, MASP-1, MASP-2 and MASP-3, and a truncated form of MASP-2 (small MBL-associated protein; sMAP or MAp19) complex with MBL to activate the lectin pathway of the complement system
- MASP-3 is an alternatively spliced product from the MASP-1 gene
- The heavy/A chains are identical between MASP-1 and MASP-3 but the light/B chains are entirely different
- Activated MASPs subsequently cleave and activate downstream components of the complement pathway.