PIMA534682

KDM5A Recombinant Rabbit Monoclonal Antibody (JB36-60), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA534682-Each-of-1 In Stock ₹ 47,036.50

PIMA534682 - Each of 1

₹ 47,036.50

In Stock

Quantity

1

Base Price: ₹ 47,036.50

GST (18%): ₹ 8,466.57

Total Price: ₹ 55,503.07

Antigen

KDM5A

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P29375

Gene Symbols

KDM5A

Immunogen

Recombinant protein within Human KDM5A aa 1,360-1,690

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Western Blot

Clone

JB36-60

Conjugate

Unconjugated

Gene

KDM5A

Gene Alias

AA409370; C76986; histone demethylase JARID1A; JARID1A; jumonji, AT rich interactive domain 1A (Rbp2 like); Jumonji, AT rich interactive domain 1A (RBP2-like); jumonji/ARID domain-containing protein 1A; Kdm5a; lysine (K)-specific demethylase 5A; lysine demethylase 5A; lysine-specific demethylase 5A; Rbbp2; RBBP-2; RBP2; retinoblastoma binding protein 2; retinoblastoma-binding protein 2

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

5927

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles, store in dark

Form

Liquid

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Description

  • Positive Control: A549, SiHa, SH-SY-5Y
  • UPF3B is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance
  • The protein is one of two functional homologs to yeast Upf3p
  • This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein
  • It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctionsThis gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance
  • The encoded protein is one of two functional homologs to yeast Upf3p
  • mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD)
  • When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons
  • This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein
  • It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions
  • This gene is located on the long arm of chromosome X
  • Two splice variants encoding different isoforms have been found for this gene.