RANGAP1 Recombinant Rabbit Monoclonal Antibody (JG37-41), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA534762-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA534762 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
RANGAP1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P46060
Gene Symbols
RANGAP1
Immunogen
Synthetic peptide within Human RanGAP1 aa 1-50
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
JG37-41
Conjugate
Unconjugated
Gene
RANGAP1
Gene Alias
C79654; fug1; KIAA1835; MGC20266; mKIAA1835; RAN GTPase activating protein 1; RAN GTPase activating protein 1 a; Ran GTPase activating protein 1 b; Ran GTPase activating protein 1 L homeolog; Ran GTPase activating protein 1 S homeolog; ran GTPase-activating protein 1; RANGAP; RanGAP1; rangap1.L; rangap1.S; rangap1a; rangap1-a; rangap1b; rangap1-b; rna1p; SD; segregation distorter homolog; segregation distortion; XELAEV_18023679mg; XELAEV_18025680mg
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
5905
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Form
Liquid
Related Products
Description
- Positive Control: MCF-7, SiHa, 293, A431, 293T, rat testis tissue, human prostate tissue, mouse brain tissue, human kidney tissue
- Ran is a small signaling GTPase that is involved in nucleocytoplasmic transport
- Two additional functions of animal Ran in the formation of spindle asters and the reassembly of the nuclear envelope in mitotic cells have been recently reported
- In contrast to Ras or Rho, Ran is not associated with membranes
- Instead, the spatial sequestering of its accessory proteins, the Ran GTPase-activating protein RanGAP and the nucleotide exchange factor RCC1, appears to define the local concentration of RanGTP vs
- RanGDP involved in signaling
- Mammalian RanGAP is bound to the nuclear pore by a mechanism involving the attachment of small ubiquitin-related modifier protein (SUMO) to its C terminus and the subsequent binding of the SUMOylated domain to the nucleoporin Nup358.