PIMA534830

PEN2 Recombinant Rabbit Monoclonal Antibody (JE41-28), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA534830-Each-of-1 In Stock ₹ 47,481.50

PIMA534830 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

PEN2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q9NZ42

Gene Symbols

PSENEN

Immunogen

Recombinant protein within Human PEN2 aa 1-101

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

JE41-28

Conjugate

Unconjugated

Gene

PSENEN

Gene Alias

1700023M09Rik; gamma-secretase subunit PEN-2; hematopoietic stem/progenitor cells protein MDS033; liver regeneration-related protein LRRGT00140; LRRGT00140 mRNA; MDS033; MSTP064; Pen2; Pen-2; presenilin enhancer 2; presenilin enhancer 2 homolog; presenilin enhancer 2 homolog (C. elegans); presenilin enhancer gamma secretase subunit; presenilin enhancer gamma-secretase subunit; presenilin enhancer protein 2; presenilin enhancer, gamma-secretase subunit; Psenen; RGD1312037

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

55851

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles, store in dark

Form

Liquid

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Description

  • Positive Control: Mouse spleen tissue, rat cerebellum tissue, human tonsil tissue, human lung cancer tissue, human kidney tissue, mouse testis tissue, A549, SH-SY-5Y
  • Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein
  • Signaling by Notch receptors mediates a wide range of developmental cell fates
  • Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease
  • This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase.