EWSR1 Recombinant Rabbit Monoclonal Antibody (JE49-57), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA534868-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA534868 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
EWSR1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q01844
Gene Symbols
EWSR1
Immunogen
Recombinant protein within Human EWSR1/EWS aa 1-229
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
JE49-57
Conjugate
Unconjugated
Gene
EWSR1
Gene Alias
AC002059.7; bK984G1.4; Ewing sarcoma breakpoint region 1; Ewing sarcoma breakpoint region 1 protein; Ewing sarcoma homolog; Ewings sarcoma EWS-Fli1 (type 1) oncogene; Ews; EWS oncogene; EWS RNA binding protein 1; EWS RNA-binding protein 1; EWS RNA-binding protein variant 6; EWS-FLI1; Ewsh; EWSR1; RNA-binding protein EWS
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
2130
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Form
Liquid
Related Products
Description
- Positive Control: K562, A431, SK-BR-3, rat testis tissue, human thyroid gland tissue, human skin tissue, human breast cancer tissue, human pancreas tissue, mouse kidney tissue, mouse heart tissue
- This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport
- The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain
- Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis
- These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein
- Mutations in this gene, specifically a ttranslocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors
- Alternative splicing of this gene results in multiple transcript variants
- Related pseudogenes have been identified on chromosomes 1 and 14.