LOX Recombinant Rabbit Monoclonal Antibody (ARC0624), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA535123-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA535123 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
LOX
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P16636, P28300, P28301
Gene Symbols
LOX
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 318-417 of human LOX (P28300)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
ARC0624
Conjugate
Unconjugated
Gene
LOX
Gene Alias
AI893619; cross-linking enzyme; H-rev142; LOX; Lysyl oxidase; Lysyl oxidase (an H-rev gene with its expression down-regulated in HRAS-transformed rat 208F fibroblasts); MGC105112; protein-lysine 6-oxidase; Protein-lysine 6-oxidase, long form; Protein-lysine 6-oxidase, short form; Ras excision protein; ras recision; rrg; Rrg1; TSC-160
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16948, 24914, 4015
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Immunogen sequence: GHKASFCLED TSCDYGYHRR FACTAHTQGL SPGCYDTYGA DIDCQWIDIT DVKPGNYILK VSVNPSYLVP ESDYTNNVVR CDIRYTGHHA YASGCTISPY Lysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes
- It plays a vital role in the formation and repair of the extra cellular matrix
- As well, LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility and cellular senescence
- The secreted form of LOX is responsible for the invasive properties of hypoxic human cancer cells
- Thus, it is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases.