PIMA535558

SMC1 Recombinant Rabbit Monoclonal Antibody (ARC1095), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA535558-Each-of-1 In Stock ₹ 47,481.50

PIMA535558 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

SMC1

Classification

Monoclonal

Concentration

0.21 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q14683, Q8NDV3, Q920F6, Q9CU62

Gene Symbols

SMC1A, SMC1B

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1134-1233 of human SMC1 (Q14683)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Clone

ARC1095

Conjugate

Unconjugated

Gene

SMC1A

Gene Alias

14S cohesin SMC1 subunit; 5830426I24Rik; CDLS2; chromosome segregation protein SmcB; DKFZp686L19178; DXhXs423e; DXS423E; KIAA0178; MGC138332; mitosis-specific chromosome segregation protein like protein beta; mKIAA0178; RP6-29D12.1; Sb1.8; segregation of mitotic chromosomes 1; segregation of mitotic chromosomes b; segregation of mitotic chromosomes-like 1; SM1A; SMC; SMC (segregation of mitotic chromosomes 1)-like 1; SMC protein; SMC protein 1A; SMC protein 1B; SMC1; SMC1 (structural maintenance of chromosomes 1, yeast)-like 1; SMC1 protein; SMC1 protein cohesin subunit; SMC1 structural maintenance of chromosomes 1-like 1; SMC1 structural maintenance of chromosomes 1-like 2; Smc1a; SMC-1A; smc1a.L; smc1aa; Smc1alpha; SMC-1-alpha; SMC1alpha protein; Smc1b; SMC-1B; SMC1BETA; SMC-1-beta; SMC1L1; Smc1l2; Smcb; SMC-like 1; SMC-protein; structural maintenace of chromosomes 1B; structural maintenance of chromosomes 1; structural maintenance of chromosomes 1 like 1; structural maintenance of c

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

140557, 24061, 27127, 8243

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Immunogen sequence: TVAALALLFA IHSYKPAPFF VLDEIDAALD NTNIGKVANY IKEQSTCNFQ AIVISLKEEF YTKAESLIGV YPEQGDCVIS KVLTFDLTKY PDANPNPNEQ Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression
  • The chromo proteins are conserved in eukaryotes and lead to mitotic chromosome segregatior defects
  • This suggests a critical function of SMC family proteins in mitotic chromosome dynamics
  • SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells
  • Specifically this SMC1/SMC3 complex is responsible for sister chromatid cohesion during metaphase
  • Mutations in the gene can lead to Cornelia de Lange syndrome 2.