PIMA535569

TNNI2 Recombinant Rabbit Monoclonal Antibody (ARC1114), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA535569-Each-of-1 In Stock ₹ 47,481.50

PIMA535569 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

TNNI2

Classification

Monoclonal

Concentration

0.68 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P13412, P27768

Gene Symbols

Tnni2

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 83-182 of human Troponin I2 (Troponin I2 (TNNI2)) (P48788)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Clone

ARC1114

Conjugate

Unconjugated

Gene

Tnni2

Gene Alias

AMCD2B; DA2B; FSSV; fsTnI; TnI; TNNI2; troponin 1, type 2; troponin I; troponin I fast twitch 2; troponin I type 2 (skeletal, fast); troponin I, fast skeletal muscle; Troponin I, fast-twitch isoform; troponin I, fast-twitch skeletal muscle isoform; troponin I, skeletal, fast; troponin I, skeletal, fast 2; troponin I2, fast skeletal type; Trp1

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

21953, 29389

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Immunogen sequence: EVRVQKTSKE LEDMNQKLFD LRGKFKRPPL RRVRMSADAM LKALLGSKHK VCMDLRANLK QVKKEDTEKE RDLRDVGDWR KNIEEKSGME GRKKMFESES This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits
  • The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction
  • Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function
  • In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha
  • This protein also suppresses tumor growth in human ovarian carcinoma
  • Mutations in this gene cause myopathy and distal arthrogryposis type 2B
  • Alternatively spliced transcript variants have been found for this gene.