PIMA535625

STAT5 alpha/beta Recombinant Rabbit Monoclonal Antibody (ARC1215), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA535625-Each-of-1 In Stock ₹ 47,481.50

PIMA535625 - Each of 1

₹ 47,481.50

In Stock

Quantity

1

Base Price: ₹ 47,481.50

GST (18%): ₹ 8,546.67

Total Price: ₹ 56,028.17

Antigen

STAT5 alpha/beta

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P42229, P42230, P42232, P51692, P52632, Q62771

Gene Symbols

STAT5A, STAT5B

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 600-786 of human STAT5 (P42229)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Clone

ARC1215

Conjugate

Unconjugated

Gene

STAT5A

Gene Alias

AA959963; Mammary gland factor; mammary gland factor STAT5A; mammary gland factor STAT5B; mammary gland factor; transcription factor; MGF; Mpf; signal transducer and activator of transcription 5; Signal transducer and activator of transcription 5a; Signal transducer and activator of transcription 5B; STA5B; STAT; STAT5; Stat5a; Stat5b; transcription factor STAT5B

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20850, 20851, 24918, 25126, 6776, 6777

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Immunogen sequence: KQQAHDLLIN KPDGTFLLRF SDSEIGGITI AWKFDSPERN LWNLKPFTTR DFSIRSLADR LGDLSYLIYV FPDRPKDEVF SKYYTPVLAK AVDGYVKPQI KQVVPEFVNA SADAGGSSAT YMDQAPSPAV CPQAPYNMYP QNPDHVLDQD GEFDLDETMD VARHVEELLR RPMDSLDSRL SPPAGLF The protein encoded by this gene is a member of the STAT family of transcription factors
  • In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor-associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators
  • This protein is activated by, and mediates the responses of, many cell ligands, such as IL-2, IL-3, IL-7, GM-CSF, erythropoietin, thrombopoietin, and different growth hormones
  • Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis
  • The mouse counterpart of this gene is found to induce the expression of BCL2L1/ BCL-X(L), which suggests the antiapoptotic function of this gene in cells.