TCF12 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA596274-Each-of-1 | In Stock | ₹ 46,057.50 |
PIPA596274 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,057.50
GST (18%): ₹ 8,290.35
Total Price: ₹ 54,347.85
Antigen
TCF12
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TCF12
Gene Alias
A130037E08Rik, ALF1, bHLHb20, Class A helix-loop-helix transcription factor ME1, class B basic helix-loop-helix protein 20, CRS3, DNA-binding protein HTF4, E-box-binding protein, HEB, HEBAlt, helix-loop-helix transcription factor 4, HsT17266, HTF4, HTF-4, ME1, Meb, REB, Salivary-specific cAMP response element-binding protein alpha, SCBP alpha, SCBPA, SCBP-alpha, TCF12, TCF-12, Transcription factor 12, transcription factor HTF-4
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
21406, 25720, 6938
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
2.68 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
P51514, Q61286, Q99081
Gene Symbols
TCF12
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 443-682 of human TCF12 (NP_0031961)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: PIGSLNSNYG GSSLVASSRS ASMVGTHRED SVSLNGNHSV LSSTVTTSST DLNHKTQENY RGGLQSQSGT VVTTEIKTEN KEKDENLHEP PSSDDMKSDD ESSQKDIKVS SRGRTSSTNE DEDLNPEQKI EREKERRMAN NARERLRVRD INEAFKELGR MCQLHLKSEK PQTKLLILHQ AVAVILSLEQ QVRERNLNPK AACLKRREEE KVSAVSAEPP TTLPGTHPGL SETTNPMGHM; Positive Samples: SW620, SH-SY5Y, A-549, mouse thymus, rat testis, SKOV3, Mouse lung, Mouse brain, Mouse spleen; Cellular Location: Nucleus TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG
- TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins
- TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation
- Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells.