PIMA536016

RON Monoclonal Antibody (03), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA536016-Each-of-1 In Stock ₹ 43,031.50

PIMA536016 - Each of 1

₹ 43,031.50

In Stock

Quantity

1

Base Price: ₹ 43,031.50

GST (18%): ₹ 7,745.67

Total Price: ₹ 50,777.17

Antigen

RON

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

Q04912

Gene Symbols

MST1R

Immunogen

Recombinant Human CD136/MST1R Protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b

Applications

Flow Cytometry

Clone

03

Conjugate

Unconjugated

Gene

MST1R

Gene Alias

CD136; Cdw136; c-met-related tyrosine kinase; friend virus susceptibility 2; Fv2; Fv-2; macrophage stimulating 1 receptor; macrophage stimulating 1 receptor (c-met-related tyrosine kinase); macrophage-stimulating protein receptor; Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain; MSP receptor; Mst1r; MST1R variant RON30; MST1R variant RON62; p185-Ron; protein tyrosine kinase 8; Protein-tyrosine kinase 8; PTK8; PTK8 protein tyrosine kinase 8; receptor protein tyrosine kinase, c-met-related; RON; RON variant E2E3; Stem cell-derived tyrosine kinase; STK

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

4486

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • MST1R (RON) is a receptor tyrosine kinase involved in cell proliferation and motility
  • The protein is a membrane-spanning, disulfide-linked heterodimer, which results from cleavage of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits
  • Ligand binding results in tyrosine phosphorylation of the beta chain
  • In knockout studies, MST1R/RON (-/-) mice failed to survive past the periimplantation period
  • The MST1R/RON gene has been mapped to 3p21, a region of frequent deletion or mutation in small cell lung and renal carcinoma, and has been implicated in the progression of several epithelial cancers
  • MST1R/Ron expression has been documented in many normal human tissues
  • ESTs have been isolated from several tissue libraries, including normal colon, mouth, prostate, and testis and cancerous colon, prostate, stomach, and uteru.