PIMA536071

MSH3 Recombinant Rabbit Monoclonal Antibody (RM405), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA536071-Each-of-1 In Stock ₹ 43,921.50

PIMA536071 - Each of 1

₹ 43,921.50

In Stock

Quantity

1

Base Price: ₹ 43,921.50

GST (18%): ₹ 7,905.87

Total Price: ₹ 51,827.37

Antigen

MSH3

Classification

Monoclonal

Concentration

0.04 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.

P20585

Gene Symbols

MSH3

Immunogen

A peptide corresponding to residues near the N-terminus of human MSH3

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

RM405

Conjugate

Unconjugated

Gene

MSH3

Gene Alias

D13Em1; Divergent upstream protein; DNA mismatch repair protein Msh3; DUC1; DUG; DUP; hMSH3; Mismatch repair protein 1; MRP1; MSH3; mutS homolog 3; mutS homolog 3 (E. coli); protein repair-1; Protein repair-3; REP-1; Rep3; Rep-3

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

4437

Content And Storage

-20°C

Form

Liquid

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Description

  • Component of the post-replicative DNA mismatch repair system (MMR)
  • Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair
  • When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs
  • MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long
  • After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.