PIPA596387
MSH3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA596387-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA596387 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
MSH3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MSH3
Gene Alias
D13Em1, Divergent upstream protein, DNA mismatch repair protein Msh3, DUC1, DUG, DUP, hMSH3, Mismatch repair protein 1, MRP1, MSH3, mutS homolog 3, mutS homolog 3 (E. coli), protein repair-1, Protein repair-3, REP-1, Rep3, Rep-3
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4437
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
P20585
Gene Symbols
MSH3
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 617-761 of human MSH3 (NP_0046962)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: FNTSEEHHAD MYRSDLPNPD TLSAELHCWR IKWKHRGKDI ELPSTIYEAL HLPDIKFFPN VYALLKVLCI LPVMKVENER YENGRKRLKA YLRNTLTDQR SSNLALLNIN FDIKHDLDLM VDTYIKLYTS KSELPTDNSE TVENT; Positive Samples: SW620, HepG2, Jurkat Component of the post-replicative DNA mismatch repair system (MMR)
- Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair
- When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs
- MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long
- After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.