PIMA536938

Phospho-4EBP1 (Thr37, Thr46) Recombinant Rabbit Monoclonal Antibody (4EB1T37T46-A5), APC, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA536938-Each-of-1 In Stock ₹ 48,371.50

PIMA536938 - Each of 1

₹ 48,371.50

In Stock

Quantity

1

Base Price: ₹ 48,371.50

GST (18%): ₹ 8,706.87

Total Price: ₹ 57,078.37

Antigen

Phospho-4EBP1 (Thr37, Thr46)

Classification

Monoclonal

Conjugate

APC

Gene

EIF4EBP1

Gene Alias

4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1

Host Species

Rabbit

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

116636, 13685, 1978

Content And Storage

4° C

Form

Liquid

Applications

Flow Cytometry

Clone

4EB1T37T46-A5

Formulation

PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.

Q13541, Q60876, Q62622

Gene Symbols

EIF4EBP1

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Thr37/46 of human phospho 4E-BP1.

Quantity

100 Tests

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG κ

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Description

  • This gene encodes one member of a family of translation repressor proteins
  • The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs
  • Interaction of this protein with eIF4E inhibits complex assembly and represses translation
  • This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.