PIMA537538
SNX6 Monoclonal Antibody (335CT6.4.6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA537538-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA537538 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
SNX6
Classification
Monoclonal
Conjugate
Unconjugated
Gene
SNX6
Gene Alias
2010006G21Rik; 2610032J07Rik; 2810425K19Rik; AU018928; C85963; MSTP010; SNX6; sorting nexin 6; sorting nexin-6; Sorting nexin-6, N-terminally processed; TFAF2; TRAF4-associated factor 2; tumor necrosis factor receptor-associated factor 4(TRAF4)-associated factor 2
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
58533
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Clone
335CT6.4.6
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
Q9UNH7
Gene Symbols
SNX6
Immunogen
SNX6 recombinant protein
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Related Products
Description
- SNX6 interacts with members of the transforming growth factor-beta family of receptor serine-threonine kinases
- These receptors belong to two classes: type II receptors that bind ligand, and type I receptors that are subsequently recruited to transduce the signal
- Of the type II receptors, SNX6 was found to interact strongly with ActRIIB and more moderately with wild type and kinase-defective mutants of TbetaRII
- Of the type I receptors, SNX6 was found to interact only with inactivated TbetaRI
- SNXs 1-4 also interacted with the transforming growth factor-beta receptor family, showing different receptor preferences
- Conversely, SNX6 behaved similarly to the other SNX proteins in its interactions with receptor tyrosine kinases
- Strong heteromeric interactions were also seen among SNX1, -2, -4, and -6, suggesting the formation in vivo of oligomeric complexes
- These findings are the first evidence for the association of the SNX family of molecules with receptor serine-threonine kinases.