ACVRL1 Recombinant Rabbit Monoclonal Antibody (ARC1735), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA538212-Each-of-1 | In Stock | ₹ 47,481.50 |
PIMA538212 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,481.50
GST (18%): ₹ 8,546.67
Total Price: ₹ 56,028.17
Antigen
ACVRL1
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P37023, P80203, Q61288
Gene Symbols
ACVRL1
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 404-503 of human ACVRL1 (P37023)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
ARC1735
Conjugate
Unconjugated
Gene
ACVRL1
Gene Alias
activin A receptor like type 1, activin A receptor type II-like 1, activin A receptor type IL, activin A receptor, type II-like 1, activin A receptor, type II-like kinase 1, Activin receptor like kinase 1, activin receptor-like kinase 1, activin receptor-like kinase-1, Acvrl1, Acvrlk1, AI115505, AI427544, ALK1, ALK-1, HHT, HHT2, ORW2, R3, R-3, Serine/threonine-protein kinase receptor R3, SETHKIR, SKR3, TGF-B superfamily receptor type I, TSR-I
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11482, 25237, 94
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Positive Samples: 293T, Mouse spleen, Mouse kidney, Rat heart Immunogen sequence: VLWEIARRTI VNGIVEDYRP PFYDVVPNDP SFEDMKKVVC VDQQTPTIPN RLAADPVLSG LAQMMRECWY PNPSARLTAL RIKKTLQKIS NSPEKPKVIQ Activin A receptor type II-like 1 (ACVRL1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands
- ACVRL1, similar to other type 1 receptors, has a conserved serine-threonine kinase subdomain, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail
- Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2
- Mutations in ACVRL1 have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by the formation of bone in muscles, tendons, and other connective tissues, as well as Epicanthus.