PIMA538579

NBS1 Monoclonal Antibody (7E4A2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA538579-Each-of-1 In Stock ₹ 48,371.50

PIMA538579 - Each of 1

₹ 48,371.50

In Stock

Quantity

1

Base Price: ₹ 48,371.50

GST (18%): ₹ 8,706.87

Total Price: ₹ 57,078.37

Antigen

NBS1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

O60934, Q9JIL9

Gene Symbols

NBN

Immunogen

Purified recombinant fragment of human NBN (aa: 467-615) expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG2a

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

7E4A2

Conjugate

Unconjugated

Gene

NBN

Gene Alias

AT V1; AT V2; ATV; AT-V1; AT-V2; Cell cycle regulatory protein p95; FLJ10155; I79_012607; MGC87362; Nbn; NBS; NBS1; nibrin; Nijmegen breakage syndrome 1 (nibrin); Nijmegen breakage syndrome protein 1; Nijmegen breakage syndrome protein 1 homolog; OTTHUMP00000204088; P95; p95 protein of the MRE11/RAD50 complex; p95-NBS1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

4683, 85482

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody has been tested in indirect ELISA
  • The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex
  • This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.