PIMA541596

HSPA1L Monoclonal Antibody (2-1#), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA541596-Each-of-1 In Stock ₹ 43,387.50

PIMA541596 - Each of 1

₹ 43,387.50

In Stock

Quantity

1

Base Price: ₹ 43,387.50

GST (18%): ₹ 7,809.75

Total Price: ₹ 51,197.25

Antigen

HSPA1L

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

P34931

Gene Symbols

Hspa1l

Immunogen

Recombinant protein Heat Shock 70kDa Protein 1 Like Protein. The antigen corresponds to amino acid range 1-641 of the target protein.

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b κ

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

2-1#

Conjugate

Unconjugated

Gene

Hspa1l

Gene Alias

heat shock 10kDa protein 1-like; heat shock 70 kDa protein 1-Hom; heat shock 70 kDa protein 1L; Heat shock 70 kDa protein 1-like; Heat shock 70 kDa protein 3; heat shock 70 kDa-like protein 1; heat shock 70kD protein-like 1; heat shock 70kDa protein 1-like; Heat shock protein; heat shock protein 1-like; Heat shock protein 70-1l; heat shock protein cognate 70, testis; heat shock protein family A (Hsp70) member 1 like; heat shock-related protein hsc70t; Hsc70t; HSP70.3; HSP70-1L; Hsp70-3; HSP70-HOM; HSP70T; Hspa1l; hum70t; inducible heat shock protein 70; Msh5; Spermatid-specific heat shock protein 70

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

3305

Content And Storage

-20°C

Form

Liquid

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Description

  • In response to adverse changes in their environment, cells from many organisms increase the expression of a class of proteins referred to as heat shock proteins
  • One class of stress proteins, termed the &quotesmall heat shock proteins&quote is comprised of a diverse group of proteins from approximately15 to >30 kDa, with a single form found in yeast and human cells and multiple related forms found in higher plants
  • A direct relationship between elevated strwess protein expression and neoplasia has been suggested from studies on estrogen-induced proteins in breast cancer cells
  • In addition, Hsp27 exhibits rapid increased phosphorylation in response to various mitogens, tumor promoter (e
  • g
  • phorbol esters) and calcium ionophores
  • The expression of a 24 kDa protein was shown to correlate with steroid hormone receptor in cell lines, organs, and tumors
  • The 24 kDa estrogen-induced protein was found to be expressed at high levels in carcinoma of the breast
  • Another study has suggested that levels of the Hsp27 correlate with endometrial adenocarcinomas
  • Interestingly, the regulation of human Hsp27 by estrogens and heat shock is reminiscent of the ecdysteroid and heat shock activation of the drosophila Hsp20 genes.