Foravirumab Recombinant Human Monoclonal Antibody, Invitrogen™

Description

• Endotoxin level < 0.01EU/μg by LAL method Use a manual defrost freezer and avoid repeated freeze thaw cycles
• Store at 2 to 8 °C for one week
• Store at -20 to -80 °C for twelve months from the date of receipt
• Foravirumab is a biosimilar that targets the Rabies virus and is used for phrophylaxis
• Rabies virus (Neurotropic lyssavirus) is a member of the Rhabdoviridae family
• Rabies is a single stranded, neurotropic, negative sense RNA virus which encodes 5 proteins: a glycoprotein, a nucleoprotein, and three others
• The mature virus has a bullet shape, a protein coat, and a lipid envelope
• The outer surface of the virus is covered with thumblike glycoprotein projections 5-10 nm long and 3 nm in diameter
• The virus averages approximately 780 nm in length
• Virus infectivity is destroyed by lipid solvents
• Rabies virus is a very successful virus, with a very wide range of hosts
• It causes an acute, central nervous system infection, characterized by CNS irritation, followed by paralysis and death
• Approximately 50,000 human deaths each year are caused by rabies.