PIMA544354

CD140b (PDGFRB) Recombinant Rabbit Monoclonal Antibody (BLR081G), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA544354-Each-of-1 In Stock ₹ 14,035.30

PIMA544354 - Each of 1

₹ 14,035.30

In Stock

Quantity

1

Base Price: ₹ 14,035.30

GST (18%): ₹ 2,526.354

Total Price: ₹ 16,561.654

Antigen

CD140b (PDGFRB)

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

BBS with 0.09% sodium azide; pH 7.8-8.6

Gene Accession No.

P09619

Gene Symbols

Pdgfrb

Immunogen

Residues 33-532 (Ecd)

Quantity

10 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

BLR081G

Conjugate

Unconjugated

Gene

Pdgfrb

Gene Alias

AI528809; Beta platelet-derived growth factor receptor; beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; CD140B; CD140b antigen; IBGC4; IMF1; JTK12; KOGS; PDGF beta chain; PDGF Receptor beta; Pdgfr; Pdgfr1; PDGFR-1; PDGFRB; PDGF-R-beta; PDGFR-beta; PENTT; platelet derived growth factor receptor beta; platelet derived growth factor receptor, beta polypeptide; platelet-derived growth factor receptor 1; Platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta variant 1; Platelet-derived growth factor receptor, beta; platelet-derived growth factor receptor, beta polypeptide

Host Species

Rabbit

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

5159

Content And Storage

2-8°C

Form

Liquid

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Description

  • Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections
  • PDGFRB is a receptor tyrosine kinase and has been implicated in atherogenesis and in cell transformation by the SIS oncogene
  • These growth factors are mitogens for cells of mesenchymal origin
  • The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides
  • The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome
  • A translocation between chromosomes 5 and 12, that fuses PDGFRB (CD140b) to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.