VEGF Receptor 1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA516493-Each-of-1 | In Stock | ₹ 49,439.50 |
PIPA516493 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,439.50
GST (18%): ₹ 8,899.11
Total Price: ₹ 58,338.61
Antigen
VEGF Receptor 1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
FLT1
Gene Alias
AI323757; embryonic receptor kinase 2; Emrk2; FLT; FLT1; FLT-1; fms related tyrosine kinase 1; FMS-like tyrosine kinase 1; FMS-related tyrosine kinase 1; Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor); FRT; i21; sFlt1; soluble VEGFR 1; sVEGFR 1; Tyrosine-protein kinase FRT; tyrosine-protein kinase receptor FLT; Vascular endothelial growth factor receptor 1; vascular endothelial growth factor receptor-1; vascular permeability factor receptor; VEGF R1; VEGFR1; VEGFR-1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
14254, 2321, 54251
Content And Storage
4° C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.
P17948, P35969, P53767
Gene Symbols
FLT1
Immunogen
A synthetic peptide from the C-terminus of the Flt-1 precursor of human origin
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA5-16493 targets Flt-1 in Western blot applications and shows reactivity with mouse, Rat, and Human samples
- The PA5-16493 immunogen is a synthetic peptide from the C-terminus of the Flt-1 precursor of human origin
- FLT1 (VEGFR1) is a receptor tyrosine kinase which plays a critical role in angiogenesis
- Active angiogenesis has been found to play important role in many pathological and physiological processes, such as tumor progression, diabetic retinopathy, rheumatoid arthritis and wound healing
- May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells
- Can promote endothelial cell proliferation, survival and angiogenesis in adulthood
- Its function in promoting cell proliferation seems to be cell-type specific
- Promotes PGF-mediated proliferation of endothelial cells, proliferation of some types of cancer cells, but does not promote proliferation of normal fibroblasts (in vitro)
- Has very high affinity for VEGFA and relatively low protein kinase activity; may function as a negative regulator of VEGFA signaling by limiting the amount of free VEGFA and preventing its binding to KDR.