T-bet Recombinant Rabbit Monoclonal Antibody (BLR110H), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA544411-Each-of-1 | In Stock | ₹ 42,364.00 |
PIMA544411 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,364.00
GST (18%): ₹ 7,625.52
Total Price: ₹ 49,989.52
Antigen
T-bet
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
BBS with 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.
Q9UL17
Gene Symbols
Tbx21
Immunogen
Between 485 And 535 (C-Term)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
BLR110H
Conjugate
Unconjugated
Gene
Tbx21
Gene Alias
HGNC:11599; LOW QUALITY PROTEIN: T-box transcription factor TBX21; Tbet; T-bet; TBLYM; T-box 21; T-box expressed in T cells; T-box protein 21; T-box transcription factor 21; T-box transcription factor TBX21; TBT1; TBX21; T-cell-specific T-box transcription factor T-bet; T-PET; transcription factor TBLYM; transcription factor T-box 21
Host Species
Rabbit
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
30009
Content And Storage
2-8°C
Form
Liquid
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Description
- Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections
- T-bet, also known as TBX21, is a T-cell specific transcription factor containing a single T-box DNA-binding domain
- It controls the expression of the TH1 cytokine, interferon-gamma
- Both Th1 and Th17 cells are crucial in immune regulation and autoimmune disease development
- T-bet initiates Th1 lineage development from naive Th precursor cells and directs T cell differentiation to Th1 versus Th17
- T-bet is cooperating with Stat4 (signal tranducer and activator of transcription 4) in programming chromatin architecture for Th1 gene expression
- Genetic variations in T-bet are associated with susceptibility to aspirin-induced asthma and nasal polyps.