PIPA5115954
SP1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5115954-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA5115954 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
SP1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SP1
Gene Alias
1110003E12Rik; AA450830; AI845540; HGNC:11205; SP1; Sp1 transcription factor; Sp1-1; specificity protein 1; trans-acting transcription factor 1; transcription factor Sp1; TSFP1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20683, 24790, 6667
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
O89090, P08047, Q01714
Gene Symbols
SP1
Immunogen
A synthesized peptide derived from human SP1(Accession P08047), corresponding to amino acid residues T427-P477.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of total SP1
- SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli
- Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses
- Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation)
- Binds also the PDGFR-alpha G-box promoter
- May have a role in modulating the cellular response to DNA damage
- Implicated in chromatin remodeling
- Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter
- Plays an essential role in the regulation of FE65 gene expression.