CD56 (NCAM) Recombinant Rabbit Monoclonal Antibody (BLR152J), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA544490-Each-of-1 | In Stock | ₹ 14,035.30 |
PIMA544490 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 14,035.30
GST (18%): ₹ 2,526.354
Total Price: ₹ 16,561.654
Antigen
CD56 (NCAM)
Classification
Recombinant Monoclonal
Concentration
100 μg/mL
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 6.8-7.4
Gene Accession No.
P13591
Gene Symbols
Ncam1
Immunogen
Residues 20-318 (Ecd)
Quantity
10 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
BLR152J
Conjugate
Unconjugated
Gene
Ncam1
Gene Alias
adhesion molecule; antigen recognized by monoclonal antibody 5.1H11; Cd56; CD-56; CD56 120 kDa GPI-linked isoform; CD56 140 kDa isoform; CD56 140 kDa VASE isoform; E NCAM; E-NCAM; MSK39; N CAM1; NCAM; N-CAM; Ncam1; N-CAM-1; NCAM-1; NCAMC; NCAM-C; neural cell adhesion molecule; Neural cell adhesion molecule 1; neural cell adhesion molecule, NCAM; sCD56; sNCAM; soluble CD56; soluble NCAM
Host Species
Rabbit
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
4684
Content And Storage
2-8°C
Form
Liquid
Related Products
Description
- Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections
- CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of the immunoglobulin family that serves as an adhesive molecule and is ubiquitously expressed in the nervous system in isoforms ranging from 120-180 kDa
- CD56 is found on T cells and NK cells, and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity
- Polysialic modification results in reduction of CD56-mediated cell adhesion
- Through its extracellular region, CD56 mediates homophilic and heterophilic interactions by binding extracellular matrix components such as laminin and integrins
- CD56 is expressed on most neuroectodermal derived cell lines, tissues and neoplasms such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma
- Further, CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumors and ovarian granulosa cell tumors
- Diseases associated with CD56 dysfunction include rabies and blastic plasmacytoid dendritic cell neoplasms.