PIMA544725

TMEM43 Recombinant Rabbit Monoclonal Antibody (JE65-15), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA544725-Each-of-1 In Stock ₹ 42,720.00

PIMA544725 - Each of 1

₹ 42,720.00

In Stock

Quantity

1

Base Price: ₹ 42,720.00

GST (18%): ₹ 7,689.60

Total Price: ₹ 50,409.60

Antigen

TMEM43

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q5XIP9, Q9BTV4, Q9DBS1

Gene Symbols

TMEM43

Immunogen

Synthetic peptide within human TMEM43 aa 91-140/400.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

JE65-15

Conjugate

Unconjugated

Gene

TMEM43

Gene Alias

1200015A22Rik; ARVC5; ARVD5; EDMD7; LUMA; Protein LUMA; Tmem43; Transmembrane protein 43; UNQ2564/PRO6244

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

362401, 74122, 79188

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

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Description

  • This gene belongs to the TMEM43 family
  • Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5)
  • Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes
  • This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.