BIN1 Recombinant Rabbit Monoclonal Antibody (JE34-92), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA544806-Each-of-1 | In Stock | ₹ 44,277.50 |
PIMA544806 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,277.50
GST (18%): ₹ 7,969.95
Total Price: ₹ 52,247.45
Antigen
BIN1
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
O00499, O08839
Gene Symbols
BIN1
Immunogen
Recombinant protein within human BIN1 aa 394-593/593.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
JE34-92
Conjugate
Unconjugated
Gene
BIN1
Gene Alias
ALP-1; AMPH 2; Amph2; amphiphysin 2; amphiphysin II; amphiphysin IIamph2; amphiphysin-like; amphiphysin-like protein; AMPHL; Bin1; box dependant MYC interacting protein 1; box-dependent myc-interacting protein 1; BRAMP-2; bridging integrator 1; DKFZp547F068; MGC10367; MGC105358; myc box dependent interacting protein 1; myc box-dependent-interacting protein 1; SH3 domain-containing protein 9; SH3P9; similar to bridging integrator 1 isoform 9
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
117028, 274
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor
- Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin
- Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process
- Studies in mouse suggest that this gene plays an important role in cardiac muscle development
- Alternate splicing of the gene results in ten transcript variants encoding different isoforms
- Aberrant splice variants expressed in tumor cell lines have also been described.