PIMA547052
SARS-CoV-2 ORF7b Recombinant Rabbit Monoclonal Antibody (HL1453), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547052-Each-of-1 | In Stock | ₹ 40,317.00 |
PIMA547052 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,317.00
GST (18%): ₹ 7,257.06
Total Price: ₹ 47,574.06
Antigen
SARS-CoV-2 ORF7b
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Target Species
Virus
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
HL1453
Conjugate
Unconjugated
Gene Alias
COVID19 ORF7b
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of SARS-CoV-2 (COVID-19) ORF7b. The exact sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Store as concentrated solution
- Centrifuge briefly prior to opening vial
- The accessory proteins of coronaviruses are essential for virus-host interactions and the modulation of host immune responses|It has been reported that accessory protein ORF3a encoded by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can induce apoptosis, and accessory protein ORF6 and ORF8 could be inhibitors of the type-I interferon (IFN) signaling pathway|However, the function of accessory protein ORF7b is largely unknown|Recent studies have shown that ORF7b promoted expression of IFN-beta, TNF-alpha, and IL-6, activated type-I IFN signaling through IRF3 phosphorylation, and activated TNF alpha-induced apoptosis in HEK293T cells and Vero E6 cells [PMID: 34484133]