TRIM72 Recombinant Rabbit Monoclonal Antibody (HL1853), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547200-Each-of-1 | In Stock | ₹ 40,317.00 |
PIMA547200 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,317.00
GST (18%): ₹ 7,257.06
Total Price: ₹ 47,574.06
Antigen
TRIM72
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
A0JPQ4, Q1XH17, Q6ZMU5
Gene Symbols
TRIM72
Immunogen
Recombinant fragment of human TRIM72.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
HL1853
Conjugate
Unconjugated
Gene
TRIM72
Gene Alias
BC067209; mg53; mitsugumin 53; mitsugumin-53; RGD1562778; TRIM72; trim72 {ECO:0000250; tripartite motif containing 72; tripartite motif containing 72, E3 ubiquitin protein ligase; tripartite motif-containing 72; tripartite motif-containing protein 72; UniProtKB:Q8N4X6}
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
365377, 434246, 493829
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Store as concentrated solution
- Centrifuge briefly prior to opening vial
- Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites
- Specifically binds phosphatidylserine
- Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site
- This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation
- Probably acts upstream of the Ca(2+)-dependent membrane resealing process
- Required for transport of DYSF to sites of cell injury during repair patch formation
- Regulates membrane budding and exocytosis
- May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles.