Aurora B Monoclonal Antibody (6G2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547462-Each-of-1 | In Stock | ₹ 43,654.50 |
PIMA547462 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,654.50
GST (18%): ₹ 7,857.81
Total Price: ₹ 51,512.31
Antigen
Aurora B
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 5mM sodium azide
Gene Accession No.
Q96GD4
Gene Symbols
AURKB
Immunogen
Full length human recombinant aurora B protein expressed in and purified from E. Coli
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Canine, Equine, Human
Product Type
Antibody
Isotype
IgG1
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Clone
6G2
Conjugate
Unconjugated
Gene
AURKB
Gene Alias
Aik2; AIM1; AIM-1; AIRK2; AL022959; ARK2; ARK-2; AurB; AURKB; aurkb-sv1; aurkb-sv2; aurora 1; aurora- and IPL1-like midbody-associated protein 1; aurora B; aurora kinase B; aurora kinase B-Sv1; aurora kinase B-Sv2; aurora/IPL1-related kinase 2; aurora-1; aurora-B; aurora-related kinase 2; IPL1; PPP1R48; protein phosphatase 1, regulatory subunit 48; serine/threonine kinase; serine/threonine kinase 12; serine/threonine kinase 5; Serine/threonine-protein kinase 12; Serine/threonine-protein kinase 5; serine/threonine-protein kinase aurora-B; STK1; STK-1; Stk12; STK12; AIK2; AIM1; ARK2; IPL1; AIM-1; STK5
Host Species
Mouse
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
100073050, 479492, 9212
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- The Aurora kinases associate with microtubules during chromosome movement and segregation
- AURKB (Aurora B) localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers
- This complex functions in chromosome alignment and separation, histone modification, and cytokinesis
- CPC also includes three non-enzymatic subunits known as the inner centromere protein (INCENP), survivin, and borealin, which determine the activity, localization, stability, and possibly even the substrate specificity of AurB
- Two CPCs exist during mitosis: one containing all four members and another consisting of INCENP and AurB
- Quaternary CPC functions during chromosome alignment and cytokinesis, whereas the INCENP-AurB complex may be responsible for modifying histone H3
- AurB is overexpressed in a number of tumours, including primary breast and colon tumour samples
- Its expression in tumours seems to be linked with Aurora-A kinase, suggesting a feedback mechanism between the two proteins.