AFP Chimeric Recombinant Rabbit Monoclonal Antibody (AF5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547838-Each-of-1 | In Stock | ₹ 46,769.50 |
PIMA547838 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,769.50
GST (18%): ₹ 8,418.51
Total Price: ₹ 55,188.01
Antigen
AFP Chimeric
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% ProClin 300
Gene Accession No.
P02771
Gene Symbols
AFP
Immunogen
AF5 was prepared by immunizing female BALB/c mice with human amniotic fluid containing AFP, from a pregnancy affected by a neural tube defect, diluted and emulsified in Freund's complete adjuvant.
Quantity
200 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Western Blot
Clone
AF5
Conjugate
Unconjugated
Gene
AFP
Gene Alias
a fetoglobulin; a fetoprotein; Afp; AFPD; Alpha fetoglobulin; alpha fetoprotein; alpha-1-fetoprotein; Alpha-fetoglobulin; alpha-fetoprotein; alpha-fetoprotein precursor; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; a fetoglobulin; a fetoprotein
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
174
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG κ
Related Products
Description
- Specificity: Recognises the human Alpha-fetoprotein
- AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract and the liver during fetal life
- AFP expression in adults is often associated with hepatoma or teratoma
- However, hereditary persistence of AFP may also be found in individuals with no obvious pathology
- The protein is thought to be the fetal counterpart of serum albumin, and AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4
- AFP is found in monomeric, dimeric, and trimeric forms
- AFP can also bind to copper ions, nickel ions, fatty acids and bilirubin
- The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly
- High level of serum AFP has been identified in patients with hepatocellular carcinomas (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.