alpha-1 Antitrypsin Monoclonal Antibody (TMF1#4B5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMIA1101-Each-of-1 | In Stock | ₹ 72,268.00 |
PIMIA1101 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 72,268.00
GST (18%): ₹ 13,008.24
Total Price: ₹ 85,276.24
Antigen
alpha-1 Antitrypsin
Classification
Monoclonal
Concentration
5 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.
P01009
Gene Symbols
SERPINA1
Immunogen
Purified human a1-Antitrypsin
Quantity
1 mg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG2a
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
TMF1#4B5
Conjugate
Unconjugated
Gene
SERPINA1
Gene Alias
a-1 AT; A1A; a1-antitrypsin; A1AT; AAT; Aat2; Aat-2; alpha 1 antitrypsin; alpha-1 antitrypsin; alpha-1 protease inhibitor; Alpha-1 protease inhibitor 1; alpha-1-antiproteinase; Alpha-1-antitrypsin; alpha-1-antitrypsin (protease inhibitor); alpha-1-antitrypsin 1-1; alpha-1-antitrypsin 2; alpha-1-antitrypsin null; alpha1AT; alpha-1-protease inhibitor; alpha-1-proteinase inhibitor; Digestive Zymogen; Dom1; MGC23330; MGC9222; PI; PI1; PRO0684; PRO2209; PRO2275; protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin; protease inhibitor 1 (anti-elastase, antitrypsin, alpha-1); Protease Serine 1; serine (or cysteine) peptidase inhibitor, clade A, member 1A; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; serine (or cysteine) proteinase inhibitor, clade A (alpha-1antiproteinase, antitrypsin), member 1; serine (or cysteine) proteinase inhibitor, clade A, member 1; serine (or cysteine) proteinase inhibitor, clade A, member 1a; Serine Protease 1; serine protease inhibitor 1-1; Serine protease inhibitor A1a; serine protease inhibitor alpha 1; serine proteinase inhibitor, clade A, member 1; serpin A1; Serpin A1a; serpin family A member 1; serpin peptidase inhibitor clade A member 1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; SERPINA1; Serpina1a; Short peptide from AAT; SPAAT; Spi1; Spi1-1; Spi1-3; TRP1; TRY1
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
5265
Content And Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
Form
Liquid
Related Products
Description
- MIA1101 targets Alpha1-Antitrypsin in IP applications and shows reactivity with Human samples
- The MIA1101 immunogen is purified human a1-Antitrypsin
- MIA1101 detects Alpha1-Antitrypsin which has a predicted molecular weight of approximately 46 kDa
- MIA1101 was formerly sold as a Seradyn product
- Alpha-1-AT is synthesized in the liver and it acts as an inhibitor of proteases such as trypsin, elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin, which may be released during inflammatory reactions in the lung
- In the absence of alpha-1-AT, these enzymes are not inhibited and they may digest pulmonary parenchyma
- Alpha-1-AT deficiency is associated with chronic obstructive lung disease (emphysema) and less frequently with hepatic cirrhosis in infants and respiratory distress of the newborn
- Increase in alpha-1-AT occurs as an acute phase response to tissue necrosis and inflammation
- Serum level of alpha-1-AT is elevated in rheumatoid arthritis, bacterial infections, vasculitis, and carcinomatosis.