PIMIA1301

AFP Monoclonal Antibody (F1-6P2A8-P2B9A9), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMIA1301-Each-of-1 In Stock ₹ 67,773.50

PIMIA1301 - Each of 1

₹ 67,773.50

In Stock

Quantity

1

Base Price: ₹ 67,773.50

GST (18%): ₹ 12,199.23

Total Price: ₹ 79,972.73

Antigen

AFP

Classification

Monoclonal

Concentration

5 mg/mL

Formulation

PBS with 0.09% sodium azide; pH 7.4

Gene Accession No.

P02771, P02772

Gene Symbols

AFP

Immunogen

Purified AFP from Cord Blood

Quantity

1 mg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Immunocytochemistry, Immunoprecipitation, Radioimmune Assays (RIA), Western Blot

Clone

F1-6P2A8-P2B9A9

Conjugate

Unconjugated

Gene

AFP

Gene Alias

a fetoglobulin; a fetoprotein; Afp; AFPD; Alpha fetoglobulin; alpha fetoprotein; alpha-1-fetoprotein; Alpha-fetoglobulin; alpha-fetoprotein; alpha-fetoprotein precursor; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; a fetoglobulin; a fetoprotein

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

11576, 174

Content And Storage

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C

Form

Liquid

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Description

  • MIA1301 can be used for immunofluorescence analysis of AFP in the endoderm derived from human embryonic stem cells
  • By Western blot, MIA1301 detects endogenous AFP protein in the early hepatocye-like cells derived from human embryonic stem cells
  • MIA1301 was formerly sold as a Seradyn product
  • AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract and the liver during fetal life
  • AFP expression in adults is often associated with hepatoma or teratoma
  • However, hereditary persistence of AFP may also be found in individuals with no obvious pathology
  • The protein is thought to be the fetal counterpart of serum albumin, and AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4
  • AFP is found in monomeric, dimeric, and trimeric forms
  • AFP can also bind to copper ions, nickel ions, fatty acids and bilirubin
  • The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly
  • High level of serum AFP has been identified in patients with hepatocellular carcinomas (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.