AFP Monoclonal Antibody (P5B8), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMIA1305-Each-of-1 | In Stock | ₹ 75,739.00 |
PIMIA1305 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 75,739.00
GST (18%): ₹ 13,633.02
Total Price: ₹ 89,372.02
Antigen
AFP
Classification
Monoclonal
Concentration
1.0 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 7.4
Gene Accession No.
P02771
Gene Symbols
AFP
Immunogen
Purified AFP from Cord Blood
Quantity
1 mg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Immunocytochemistry, Immunoprecipitation, Radioimmune Assays (RIA), Western Blot
Clone
P5B8
Conjugate
Unconjugated
Gene
AFP
Gene Alias
a fetoglobulin; a fetoprotein; Afp; AFPD; Alpha fetoglobulin; alpha fetoprotein; alpha-1-fetoprotein; Alpha-fetoglobulin; alpha-fetoprotein; alpha-fetoprotein precursor; alpha-foetoprotein; chloride intracellular channel 6; FETA; fetoglobulin; fetoprotein; HPAFP; a fetoglobulin; a fetoprotein
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
174
Content And Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
Form
Liquid
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Description
- MIA1305 can be used for immunofluorescence analysis of AFP in the endoderm derived from human embryonic stem cells
- By Western blot, MIA1305 detects endogenous AFP protein in the early hepatocyte-like cells derived from human embryonic stem cells
- AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract and the liver during fetal life
- AFP expression in adults is often associated with hepatoma or teratoma
- However, hereditary persistence of AFP may also be found in individuals with no obvious pathology
- The protein is thought to be the fetal counterpart of serum albumin, and AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4
- AFP is found in monomeric, dimeric, and trimeric forms
- AFP can also bind to copper ions, nickel ions, fatty acids and bilirubin
- The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly
- High level of serum AFP has been identified in patients with hepatocellular carcinomas (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.