PIPA1112
PAX8 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA1112-Each-of-1 | In Stock | ₹ 51,620.00 |
PIPA1112 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,620.00
GST (18%): ₹ 9,291.60
Total Price: ₹ 60,911.60
Antigen
PAX8
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PAX8
Gene Alias
HGNC:8622; paired box 8; paired box gene 8; paired box protein Pax-8; paired domain gene 8; PAX8; Pax-8; Pax-8 protein
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
7849
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide
Gene Accession No.
Q06710
Gene Symbols
PAX8
Immunogen
Purified internal fragment of human recombinant PAX8 expressed in E. coli
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Non-human Primate
Product Type
Antibody
Isotype
IgG
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Description
- Western blot analysis of PA1-112 detects a prominent ∽48 kDa protein in human adenocarcinoma SKOV-3 and SV40 transformed African green monkey (Cercopithecus aethiops) kidney cells
- In SKOV-3 cells, 2 additional unknown bands at (∽20 kD) and at ∽150 kDa are also detected
- Specificity of the antibody was confirmed in HeLa and 293T cells overexpressing full lenght PAX8
- The 48 kDa band is enriched in immunoprecipitations from Cos7 lysate, however additional unknown high molecular weight bands are also enriched and detected by PA1-112
- This gene encodes a member of the paired box family of transcription factors
- Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain
- This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes
- Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas
- Alternatively spliced transcript variants encoding different isoforms have been described.