PIPA1117

PAX7 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA1117-Each-of-1 In Stock ₹ 48,282.50

PIPA1117 - Each of 1

₹ 48,282.50

In Stock

Quantity

1

Base Price: ₹ 48,282.50

GST (18%): ₹ 8,690.85

Total Price: ₹ 56,973.35

Antigen

PAX7

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PAX7

Gene Alias

FLJ37460; HUP1; paired box 7; paired box gene 7; paired box homeotic gene 7; paired box protein Pax-7; paired box transcription factor PAX7; paired domain gene 7; PAX7; Pax-7; PAX7 transcriptional factor; PAX7A; PAX7B; RGD1564360; RMS2

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

18509, 5081

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide

Gene Accession No.

P23759, P47239

Gene Symbols

PAX7

Immunogen

Purified internal fragment of human recombinant PAX7 expressed in E. coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Western blot analysis of PA1-117 detects a prominent ∽54 kDa protein in human HeLa, MCF7, rhabdomyosarcoma and skeletal muscle satellite cells and a weaker ∽57 kDa protein in HeLa, rhabdomyosarcoma and skeletal muscle satellite cells
  • The ∽57 kDa band seems to be enriched in immunoprecipitations from HeLa lysate, suggesting a bias for the larger isoform in ths application
  • Weak unknown bands of lower molecular weight and at ∽110-130 kDa are also detected
  • Specificity of the antibody was also confirmed in Hela cells overexpressing full length PAX7
  • This gene is a member of the paired box (PAX) family of transcription factors
  • Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain
  • These genes play critical roles during fetal development and cancer growth
  • The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma
  • Three transcript variants encoding different isoforms have been found for this gene.