PIPA112928

Lass4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA112928-Each-of-1 In Stock ₹ 48,905.50

PIPA112928 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

Lass4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CERS4

Gene Alias

2900019C14Rik; Ceramide synthase 4; CerS4; FLJ12089; LAG1 homolog, ceramide synthase 4; LAG1 longevity assurance homolog 4; Lass4; longevity assurance homolog 4; Sphingosine N-acyltransferase CERS4; TRAM homolog 1; translocating chain-associating membrane protein homolog 1; Trh1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

79603

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.08% sodium azide

Gene Accession No.

Q9HA82

Gene Symbols

CERS4

Immunogen

Synthetic peptide corresponding to human Lass4 protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control for this product is lung or embryo lysate
  • The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals
  • Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis
  • LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein
  • LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides
  • In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis.