PIPA120644

AVPR2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA120644-Each-of-1 In Stock ₹ 49,083.50

PIPA120644 - Each of 1

₹ 49,083.50

In Stock

Quantity

1

Base Price: ₹ 49,083.50

GST (18%): ₹ 8,835.03

Total Price: ₹ 57,918.53

Antigen

AVPR2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AVPR2

Gene Alias

ADHR; antidiuretic hormone receptor; arginine vasopressin receptor 2; Avp2r; AVPR V2; AVPR2; DI1; DIR; DIR3; MGC126533; MGC138386; ND1; NDI; nephrogenic diabetes insipidus; renal-type arginine vasopressin receptor; V2R; V2-renal V2R; Vasopressin receptor V2; vasopressin V2 receptor; VPV2R

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

554

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 0.1% sodium azide

Gene Accession No.

P30518

Gene Symbols

AVPR2

Immunogen

Synthetic 15 amino acid peptide from C-terminus of human AVPR2

Quantity

25 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Avpr2 is a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin 2 and a glycopeptide, copeptin
  • Arginine vasopressin is a posterior pituitary hormone which is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus
  • Along with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream
  • The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary
  • Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems
  • Avpr2 has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels
  • Avpr2 can contract smooth muscle during parturition and lactation
  • Avpr2 is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions
  • The activity of Avpr2 is mediated by G proteins which activate adenylate cyclase.