PIPA121361

IL-22 Receptor alpha Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA121361-Each-of-1 In Stock ₹ 49,083.50

PIPA121361 - Each of 1

₹ 49,083.50

In Stock

Quantity

1

Base Price: ₹ 49,083.50

GST (18%): ₹ 8,835.03

Total Price: ₹ 57,918.53

Antigen

IL-22 Receptor alpha

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Il22ra1

Gene Alias

9130219A07Rik; CRF2-9; Cytokine receptor class-II member 9; cytokine receptor family 2 member 9; ENSMUSG00000073746; il-22 receptor; IL-22 receptor subunit alpha-1; IL22R; IL-22R; IL22R1; IL22RA1; IL-22RA1; IL-22R-alpha-1; ILN; Interleukin; interleukin 22 receptor subunit alpha 1; interleukin 22 receptor, alpha 1; interleukin-22 receptor alpha chain; interleukin-22 receptor subunit alpha-1; RGD1559655; zcytoR11

Host Species

Goat

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

58985

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

10mM potassium phosphate with 140mM NaCl, 1mg/mL BSA and 0.1% sodium azide

Gene Accession No.

Q8N6P7

Gene Symbols

Il22ra1

Immunogen

Synthetic peptide of Human IL22 Receptor N terminal amino acids 42-70 [DSGPEGTPDTVYSIEYKTYGERDWVAKK]

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: Human spleen or tonsil
  • A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified
  • The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family
  • IL-22R forms a complex with IL-10 receptor beta chain and mediates IL-22 signaling
  • IL-22 and its receptor activate JAK-STAT signaling pathway
  • IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10
  • A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-alpha 2 (IL-22RA2), was identified very recently
  • IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity
  • LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.