Dysadherin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA131506-Each-of-1 | In Stock | ₹ 49,439.50 |
PIPA131506 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,439.50
GST (18%): ₹ 8,899.11
Total Price: ₹ 58,338.61
Antigen
Dysadherin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
FXYD5
Gene Alias
DYSAD; Dysadherin; EF-8; FXYD domain containing ion transport regulator 5; FXYD domain-containing ion transport regulator 5; FXYD5; HSPC113; Ion channel homolog RIC; IWU1; IWU-1; KCT1; keratinocytes associated transmembrane protein 1; OIT2; oncoprotein induced transcript 2; oncoprotein-induced protein 2; PRO6241; RIC; UNQ2561/PRO6241
Host Species
Goat
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
53827
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q96DB9
Gene Symbols
FXYD5
Immunogen
synthetic peptide GKCRQLSRLCRNHCR (Human).
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX22248-PEP).
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 in variant and 6 highly conserved amino acids
- The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator
- Mouse FXYD5 has been termed RIC (Related to Ion Channel)
- FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme
- FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems
- Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane
- This gene product, FXYD5, is a glycoprotein that functions in the up-regulation of chemokine production, and it is involved in the reduction of cell adhesion via its ability to down-regulate E-cadherin
- It also promotes metastasis, and has been linked to a variety of cancers
- Alternative splicing results in multiple transcript variants.