Fe65 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA146191-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA146191 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Fe65
Classification
Polyclonal
Conjugate
Unconjugated
Gene
APBB1
Gene Alias
adaptor protein FE65a2; amyloid beta (A4) precursor protein-binding, family B, member 1; amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65); amyloid beta A4 precursor protein-binding family B member 1; amyloid beta precursor protein binding family B member 1; Amyloid-beta A4 precursor protein-binding family B member 1; APBB1; FE65; MGC:9072; Protein Fe65; RIR; stat-like protein
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11785, 29722, 322
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
1.3 mg/mL
Formulation
PBS with 15% glycerol and 0.02% sodium azide
Gene Accession No.
O00213, P46933, Q9QXJ1
Gene Symbols
APBB1
Immunogen
Recombinant rat protein expressed in bacteria.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Suggested positive control: IMR32 neuronal cell lysate, HEK 293 cell lysate, or brain lysate, antigen standard for APBB1 (transient overexpression lysate)
- The protein encoded by this gene is a member of the Fe65 protein family
- It is an adaptor protein localized in the nucleus
- It interacts with the Alzheimer's disease amyloid precursor protein, transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein
- APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation
- This encoded protein could play an important role in the pathogenesis of Alzheimer's disease
- It is thought to regulate transcription
- Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression
- Multiple alternatively spliced transcript variants have been described for this gene but some of their full length sequence is not known.